Van de Ven Double Halts Everton's Unbeaten Streak at New Home Ground
Micky van de Ven became the initial backline player to score two goals in a English top-flight match for Spurs since Jan Vertonghen in March 2013.
Match summary
Micky Van de Ven nods home two times in first half
The home side's Jake O'Brien has goal ruled after VAR review
Senegalese midfielder scores final goal in dying moments
This loss is the Merseyside club's first at Hill Dickinson Stadium
The Tottenham defender scored on two occasions as Tottenham prolonged their winning streak in away games in the Premier League and delivered Everton their initial loss at Hill Dickinson Stadium.
Everton were undefeated in their last five matches at their recently opened stadium at the dockside location, having left Goodison Park behind after 133 years at the conclusion of the previous campaign.
But Tottenham's leader the Dutchman struck twice from set-pieces in the opening 45 minutes to put their impressive record at jeopardy, and they were unable to turn it around before Pape Matar Sarr - set up by ex-Everton forward Richarlison - nodded in a final goal to put the game to bed.
The Everton defender thought he had levelled the scores five minutes after Van de Ven's first goal, glancing a powerful header past Guglielmo Vicario from an Everton corner.
The Portuguese striker, in the meantime, missed a number of opportunities, while the Italian goalkeeper made a series of excellent saves to guarantee Tottenham went five matches on the road unbeaten in the Premier League.
But the VAR stepped in, instructing the match official to review the score on the pitchside monitor and the official ruled that Jack Grealish and Iliman Ndiaye were in an illegal position and had impeded with the Tottenham goalkeeper.
This victory elevates Thomas Frank's side into third place in the division, five points off north London rivals and leaders Arsenal.
Everton stay in 14th position and sit six points ahead of the drop zone.
Spurs breakdown: The defender excels in duties at each end of pitch
Following a drab weekday display in the Champions League against the French side, where they managed a mere two shots on goal, the manager chose Randal Kolo Muani in attack instead of ex-Everton forward the Brazilian.
The new arrival was unable to influence the game before being replaced for the substitute after an hour on the field, but it turns out he wasn't needed in the end.
Defender the Dutchman transformed into an attacking force to be reckoned with.
Spurs' opening strike came from a cleverly executed set-piece play, with the midfielder heading the ball toward the face of goal for an free Van de Ven to head home.
And the captain - stepping up as captain in the Argentine's absence - added his second in added time as he outjumped Jordan Pickford to head home.
The Dutchman was just as outstanding in defence, combining well with Kevin Danso as the pair dealt excellently with the 34 crosses thrown their way by the opposition.
Toffees breakdown: Toffees missing striker's instinct
Everton's new home had been a happy hunting ground, but it appears the freshness may have worn off slightly and fans flocked to the exits after the midfielder's final goal for Tottenham.
The end in the team's unbeaten home run won't be a major concern for the manager, but their striker situation will be.
The forward and Thierno Barry - the Toffees' two established centre-forwards - had scored only one league goal between them before the weekend's outing.
And they were unable to add to that miserable record on a wet and gloomy evening on Merseyside.
The striker's performance was summed up when he opted to bicycle-kick a clear chance from near the goal, despite having room and opportunity to readjust for a more conventional shot that would have tested the keeper.
The substitute, too, failed to make an impact after coming on for the starter in the 65th minute.
It wasn't for a lack of chance. The majority of Everton's attacks came through the winger and Ndiaye, who relentlessly whipped dangerous crosses into the Tottenham penalty area.
What next for both teams?
The Toffees: The team travel to Sunderland in the top flight on early November at 20:00 GMT.
Tottenham: Spurs travel to Newcastle's ground on Wednesday, 29 October for their next round League Cup match against Newcastle.